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在局部血管张力调节方面,血管内皮的重要作用已被充分认识.内皮细胞可产生几种血管活性物质,如现已推测为氧化氮的内皮松弛因子,以及诸如血栓素A_2(TXA_2)和内皮素-1(ET-1)的血管收缩剂.
The important role of the vascular endothelium in the regulation of local vascular tone is well understood.Endothelial cells produce several vasoactive substances such as endothelial relaxants that have been postulated to be nitric oxide as well as endothelium-dependent factors such as thromboxane A 2 (TXA 2) and endothelin -1 (ET-1) vasoconstrictor.