原发性骨髓纤维化是一种骨髓增生性疾病,又称组织髓样化生,骨髓硬化症、具有髓样化生的骨髓硬化症(Myeloscleosis With myeloid metaplasia)、原因不明性髓样化生及原因不明性髓化造血等,多见于40岁以上的成人,小儿罕见。国外文献至1975年报道的小儿病例不足30例,国内 Primary myelofibrosis is a myeloproliferative disease, also known as myeloid metaplasia, myelosclerosis, myeloid myeloid metaplasia, unexplained myeloid metaplasia and Unidentified reasons such as hematopoietic haematopoietic, more common in adults over the age of 40, rare in children. Foreign literature reported in 1975 to less than 30 cases of pediatric, domestic