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目的观察应用玻璃酸钠的复合小梁切除术治疗前葡萄膜炎继发青光眼的临床疗效。方法 观察组共37例(37眼)前葡萄膜炎继发青光眼,经药物治疗眼压仍不能控制而行复合小梁切除术,术中向巩膜瓣下及前房内注入玻璃酸钠0.2 mL;以同期行复合小梁切除术的29例(29眼)前葡萄膜炎继发青光眼作为对照,术中于巩膜瓣下及前房内注入0.2 mL平衡盐溶液。术后监测并记录视力、眼压、前房深度、前房角及滤过泡情况,随访9～15个月。结果与对照组比较,观察组手术成功率及功能性滤过泡比率较高,滤过瘘口开放较好,术后早期浅前房发生率较低,差异有统计学意义(P<0.05)。两组间视力改善差异无显著性(P>0.05)。结论对前葡萄膜炎继发青光眼行复合小梁手术,应用玻璃酸钠能减少滤过道黏连,明显提高手术质量及成功率。
Objective To observe the clinical effect of sodium hyaluronate combined trabeculectomy in the treatment of glaucoma secondary to anterior uveitis. Methods A total of 37 patients (37 eyes) with anterior glaucoma secondary to glaucoma were treated with compound trabeculectomy under intraocular pressure (IOP). Intraoperatively, 0.2 mL of sodium hyaluronate 29 cases (29 eyes) with anterior glaucoma secondary glaucoma treated with compound trabeculectomy as control were injected intraperitoneally with 0.2 ml of balanced salt solution under scleral flap and anterior chamber. Postoperative monitoring and recording of visual acuity, intraocular pressure, anterior chamber depth, anterior chamber angle and filtration bleb conditions, followed up for 9 to 15 months. Results Compared with the control group, the successful rate of operation and the rate of functional bleb in the observation group were higher, the fistula opening was better, and the incidence of the shallow anterior chamber was lower in the early postoperative period (P <0.05) . There was no significant difference in visual acuity between the two groups (P> 0.05). Conclusion Combined trabeculectomy with glaucoma secondary to anterior uveitis may reduce the adhesion of the filter tract and improve the quality and success rate of the operation.