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目的观察阿奇霉素联合阿莫西林/克拉维酸治疗重症社区获得性肺炎的临床疗效。方法将115例患者随机分为三组:A组36例,阿奇霉素针500 mg/d;B组40例,阿莫西林/克拉维酸针4.8 g/d;C组39例,阿奇霉素针500 mg/d和阿莫西林/克拉维酸针4.8 g/d。观察临床有效率,并对结果进行统计学分析。结果C组有效率(89.7%)明显高于A组(69.4%)和B组(70.0%)。结论阿奇霉素联合阿莫西林/克拉维酸治疗重症社区获得性肺炎优于上述单种抗生素治疗疗效。
Objective To observe the clinical efficacy of azithromycin combined with amoxicillin / clavulanic acid in the treatment of severe community-acquired pneumonia. Methods One hundred and fifteen patients were randomly divided into three groups: group A 36 cases, azithromycin 500 mg / d, group B 40 cases, amoxicillin / clavulanate 4.8 g / d, group C 39 cases, azithromycin 500 mg / d and amoxicillin / clavulanate 4.8 g / d. Clinical efficiency was observed and the results were statistically analyzed. Results The effective rate (89.7%) in group C was significantly higher than that in group A (69.4%) and group B (70.0%). Conclusion Azithromycin combined with amoxicillin / clavulanic acid treatment of community-acquired severe pneumonia is better than the single antibiotic treatment.