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目的观察凝血酶联合奥美拉唑对残胃出血的临床治疗效果。方法选取江西省宜春市上高县中医院收治的60例残胃出血患者,随机均分为实验组(凝血酶2000U和15mL生理盐水进行配置,口服,2次/d;奥美拉唑每次静脉注射40mg,2次/d)和对照组(出血量较大患者应进行静脉补血,给予维生素等止血药物,抗感染治疗等)(n=30)。治疗后比较2组患者的治疗总有效率和不良反应发生率。结果治疗后实验组总有效率为93.3%,显著高于对照组的63.3%(P<0.05)。实验组不良反应发生率为13.3%,低于对照组的16.7%。结论对实施胃大部切术后残胃出血的患者,采用凝血酶联合奥美拉唑能够显著提高患者的临床疗效,且不良反应发生率低。
Objective To observe the therapeutic effect of thrombin combined with omeprazole on residual gastric hemorrhage. Methods Sixty patients with residual gastric hemorrhage admitted to Shanggao Chinese Medicine Hospital of Yichun City of Jiangxi Province were randomly divided into experimental group (2000U for thrombin and 15mL of saline for oral administration, 2 times / d); omeprazole Intravenous injection of 40mg, 2 times / d) and control group (patients with larger bleeding should be venous blood, given vitamins and other hemostatic drugs, anti-infective therapy, etc.) (n = 30). After treatment, the total effective rate of treatment and the incidence of adverse reactions in the two groups were compared. Results After treatment, the total effective rate of the experimental group was 93.3%, which was significantly higher than that of the control group (63.3%, P <0.05). The incidence of adverse reactions in the experimental group was 13.3%, which was lower than 16.7% of the control group. Conclusion In patients with residual gastric remnant after gastrectomy, the combination of thrombin and omeprazole can significantly improve the clinical efficacy of patients, and the incidence of adverse reactions is low.