冷凝集素病(Cold agglutinin disease)旧称可逆性低温血凝集症。1890年首先由Reitmann报告,国内1952～1966年间屡见个案报告,共47例,加上本文1例,共48例。现将本例报告如下。 病历摘要 患者,男,62岁,河北人,在西安市工作。主诉遇冷时四肢末端、鼻尖、耳轮、口唇青紫,伴麻木刺痛约1年余,于1977年4月6日入院。缘于1976年1月发觉遇冷时四肢末端、耳轮、口唇等暴露部位青 Cold agglutinin disease formerly known as reversible hypothermia hemagglutination. Reitmann first reported in 1890, the domestic frequent case reports from 1952 to 1966, a total of 47 cases, with this article in 1 case, a total of 48 cases. This case report is as follows. Patient summary, male, 62 years old, Hebei, working in Xi’an. When the chief complaint of cold extremities end, nose, ear, lips bruising, stinging with numb for about 1 year, in April 6, 1977 admission. Due to the discovery in January 1976 when extremities extremities, ear, lips and other exposed parts of blue