国内文献对应用甲哨唑毒副作用的报道不多,且报道多限于消化系统方面,如食欲不振,腹胀、恶心,腹部绞痛,或者神经系统的头痛、头晕等。我科近期发生1例因应用甲哨唑诱发癲痫发作的病例,现报道如下。患者男性,20岁,因反复发作右下腹痛1月,加重3天于1989年7月1日入院。入院时一般状况较差,急性病容,腹部体征呈典型的急性腹膜炎表现,急诊手术。术后应用甲哨唑配合其它抗菌素治疗腹腔内感染。因体温持续不降,腹腔渗液较多,所以,维持使用甲哨唑共计26天,剂量为0.5g,2/日,静滴。患者于用药后第20天及28天时2次突发癲痫 The domestic literature on the side effects of mew terazole toxicity reported little, and the report is limited to the digestive system, such as loss of appetite, bloating, nausea, abdominal cramps, or nervous system headache, dizziness and so on. A case of recent occurrence of epilepsy in our department due to the application of methadone, are reported below. Male patient, 20 years old, because of recurrent lower right abdominal pain in January, increased 3 days in July 1, 1989 admission. Admission generally poor condition, acute illness, abdominal signs showed a typical acute peritonitis performance, emergency surgery. Postoperative application of methadone with other antibiotics in the treatment of intra-abdominal infection. Due to continued body temperature drop, peritoneal effusion more, so to maintain the use of metostezole a total of 26 days, a dose of 0.5g, 2 / day, intravenous infusion. Patients in the first 20 days and 28 days after the onset of 2 epilepsy