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目的了解阿莫西林的临床不良反应。方法回顾性分析本院2011年12月~2013年12月收治的67例使用阿莫西林治疗后出现不良反应患者的临床资料,探究患者给药状况、使用剂量与不良反应及治疗、转归等具体情况。结果临床上较为常见的是皮肤过敏与过敏性休克,幻觉、腹痛、瘙痒、血尿以及死亡等较为少见,阿莫西林不良反应易发于治疗期间与治疗后。67例患者经治疗出现2例(2.99%)死亡,65例患者临床症状均消失,治愈率达97.01%。结论在阿莫西林使用中,要把握其适应证与禁忌证,坚持合理用药,强化临床观察,避免发生不良反应。
Objective To understand the clinical adverse effects of amoxicillin. Methods The clinical data of 67 patients who had adverse reactions after amoxicillin treatment from December 2011 to December 2013 in our hospital were analyzed retrospectively to investigate the patients’ medication status, dosage, adverse reactions, treatment and prognosis specific situation. Results Clinically, skin allergies and anaphylactic shock, hallucinations, abdominal pain, pruritus, hematuria and death were more common. Adverse reactions to amoxicillin were more likely to occur during and after treatment. 67 patients died after treatment in 2 cases (2.99%), 65 patients disappeared clinical symptoms, the cure rate was 97.01%. Conclusion In the use of amoxicillin, we must grasp the indications and contraindications, adhere to the rational use of drugs, strengthen clinical observation, to avoid adverse reactions.