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目的:探讨糖皮质激素在治疗小儿急性上呼吸道感染中的临床疗效及需注意的问题。方法:将在我院接受治疗且诊断为急性上呼吸道感染的96例患儿,随机平均分为两组。对照组采用常规治疗措施,观察组在常规治疗措施基础上,应用糖皮质激素雾化吸入治疗,对比两组患儿的临床效果。结果:观察组显效19(39.58%)例,有效28(58.33%)例,无效1(2.09%)例,总有效率为97.91%。对照组显效15(31.25%)例,有效25(52.08%)例,无效8(16.67%)例,总有效率为83.33%。经过比较,两组患儿总有效率,差异具有显著性(P<0.05),且观察组明显优于对照组。观察组共有9例患儿出现并发症,其中支气管炎7(14.58%)例,肺炎2(4.17%)例,并发症发生率为18.75%。对照组共有4例患儿出现并发症,其中支气管炎4(8.33%)例,肺炎0(0.00%)例,并发症发生率为8.33%。两组患儿并发症发生率,差异具有显著性(P<0.05),且观察组明显高于对照组。结论:糖皮质激素可有效治疗小儿急性上呼吸道感染,但在临床治疗过程中,临床医生应权衡利弊,严密观察糖皮质激素的并发症,做到正确应用。
Objective: To investigate the clinical effect of glucocorticoids in the treatment of acute upper respiratory tract infection in children and pay attention to it. Methods: Ninety-six children diagnosed with acute upper respiratory tract infection who were treated in our hospital were randomly divided into two groups. In the control group, conventional treatment was used. The observation group was treated with inhaled corticosteroid atomization on the basis of routine treatment measures, and the clinical effect of the two groups was compared. Results: The effective rate of observation group was 19 (39.58%), effective 28 (58.33%) and ineffective 1 (2.09%), the total effective rate was 97.91%. In the control group, 15 (31.25%) cases were markedly effective, 25 (52.08%) cases were effective, and 8 (16.67%) cases were ineffective. The total effective rate was 83.33%. After comparison, the two groups of children with total efficiency, the difference was significant (P <0.05), and the observation group was significantly better than the control group. A total of 9 patients in the observation group had complications, including 7 cases of bronchitis (14.58%) and 2 cases of pneumonia (4.17%), the complication rate was 18.75%. A total of 4 children in the control group had complications, including 4 cases of bronchitis (8.33%) and 0 cases of pneumonia (0.00%), with a complication rate of 8.33%. The incidence of complications in both groups was significant (P <0.05), and the observation group was significantly higher than the control group. Conclusion: Glucocorticoids can effectively treat children with acute upper respiratory tract infection. However, clinicians should weigh the pros and cons and carefully observe the complications of glucocorticosteroids for correct application.