本文比较轻～中度原发性高血压患者和血压正常健康志愿者短期或长期服用维拉帕米或硝苯啶对血压、心率、血浆儿茶酚胺浓度和肾素活性、血浆容量以及心功能的影响.WHO分类Ⅰ～Ⅱ期的原发性高血压患者53(男32、女21)例,年龄22～58(平均38)岁,血压150～190/95～130mmHg,停止原先治疗至少4周后参加试验.另有15[男9、女5(原文如此)]例正常人,年龄24～41(平均30)岁.短期试验住院进行,按单盲法给药.22例患者 This article compares the effect of short-term or long-term use of verapamil or nifedipine on blood pressure, heart rate, plasma catecholamine concentrations, renin activity, plasma volume, and cardiac function in patients with mild to moderate essential hypertension and normotensive hypertensive volunteers .WHO classification Ⅰ ~ Ⅱ period of 53 cases of essential hypertension (male 32, female 21), aged 22 to 58 (average 38) years old, blood pressure 150 ~ 190/95 ~ 130mmHg, stop the original treatment for at least 4 weeks Another 15 [male 9, female 5 (the original text so]] normal cases, aged 24 to 41 (average 30) years of age. Short-term trials hospitalized, blinded by single blind method .22 patients