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目的探讨药源性低钾血症的疾病特点,为临床早期诊断和治疗提供依据。方法回顾分析2009年1月1日至2011年1月1日期间收治的58例药源性低钾血症住院患者的临床资料。结果本组药源性低钾血症患者中,男性25例,女性23例;年龄35～83岁,平均年龄56.8岁;胰岛素类(39.7%)导致的药源性低血钾反应居首位,其次为利尿药(20.7%)、泻药(17.2%)、抗生素(13.8%)。本组患者通过及时补钾治疗均痊愈。结论药源性低钾血症的诊断,必须具备相关药物的用药史,再结合症状、体征、血钾及心电图检查等进行综合分析判断。
Objective To investigate the characteristics of drug-induced hypokalemia and provide the basis for early clinical diagnosis and treatment. Methods The clinical data of 58 hospitalized patients with drug-induced hypokalemia admitted from January 1, 2009 to January 1, 2011 were retrospectively analyzed. Results The group of drug-induced hypokalemia patients, 25 males and 23 females; aged 35 to 83 years, mean age 56.8 years; insulin (39.7%) lead to drug-induced hypokalemia response first place Followed by diuretics (20.7%), laxatives (17.2%) and antibiotics (13.8%). This group of patients through timely potassium treatment were cured. Conclusion The diagnosis of drug-induced hypokalemia must be related to drug history, combined with symptoms, signs, serum potassium and ECG analysis to determine a comprehensive analysis.