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目的分析十二指肠溃疡合并胃癌的临床病理特点。方法选取十二指肠溃疡合并胃癌患者41例的临床资料进行分析。结果合计41例十二指肠溃疡合并胃癌患者,占同期十二指肠溃疡的0.99%。41例中,男性占70.73%;>50岁者占80.49%;十二指肠溃疡位于球部占90.24%;溃疡分期以S2期多见,占51.22%;胃癌位于胃窦占51.22%,其次为胃体,占36.59%,内镜下分型进展期癌占92.68%;按Bormann分型Ⅱ型占80.49%;病理分型以中分化腺癌多见,占70.73%,其次为低分化腺癌,占12.20%;快速尿素酶试验阳性者占82.93%。结论十二指肠溃疡合并胃癌患者病理分型以中分化腺癌多见,多为进展期,对十二指肠溃疡患者应加强内镜随访,以提高该类患者的胃癌诊断率。
Objective To analyze the clinicopathological features of duodenal ulcer complicated with gastric cancer. Methods The clinical data of 41 patients with duodenal ulcer and gastric cancer were analyzed. Results A total of 41 cases of duodenal ulcer with gastric cancer patients, accounting for 0.99% of duodenal ulcers in the same period. Among 41 cases, 70.73% were male, 80.49% were patients> 50 years old, 90.24% were duodenal ulcer located in the bulb, 51.22% were seen in stage S2 gastric ulcer, 51.22% Accounting for 36.59% of gastric body and 92.68% of advanced carcinoma under endoscopy. According to Bormann classification, type Ⅱ accounted for 80.49%. Pathological type was more common in moderately differentiated adenocarcinoma (70.73%), followed by poorly differentiated adenocarcinoma Cancer, accounting for 12.20%; rapid urease test positive accounted for 82.93%. Conclusions The pathological type of duodenal ulcer with gastric cancer is more common in moderately differentiated adenocarcinoma and mostly in advanced stage. Endoscopic follow-up should be strengthened in patients with duodenal ulcer so as to improve the diagnosis rate of gastric cancer in these patients.