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目的:分析并探讨小儿幽门螺杆菌感染与缺铁性贫血的相关性。方法:选择2012年2月至2013年2月本院门诊患儿412例,行血常规、血清铁、血清铁蛋白、HP-IgG抗体检测。结果:HP感染患儿IDA26例,IDA患病率为20.4%(26/127),HP未感染患儿IDA19例,IDA患病率为6.7%(19/285)。两者比较差异有统计学意义(x2=17.21,P=0.00)。对比两组患儿MCV、MCH、MCHC指标,差异具有显著性(P均<0.05)。45例IDA患儿中26例有HP感染,感染率为57.8%(26/45),367例非IDA患儿中有101例HP感染,感染率为27.5%(101/367)。两者比较差异有统计学意义(x2=17.21,P=0.00)。结论:HP感染同IDA发病有显著相关性,HP感染可以是导致IDA的原因。
Objective: To analyze and discuss the relationship between Helicobacter pylori infection in children and iron deficiency anemia. Methods: From February 2012 to February 2013, 412 outpatients in our hospital were selected for blood routine examination, serum iron, serum ferritin and HP-IgG antibody. Results: There were 26 IDA cases in HP infected children, the IDA prevalence rate was 20.4% (26/127), HPD uninfected children IDA19 cases, IDA prevalence rate was 6.7% (19/285). The difference between the two was statistically significant (x2 = 17.21, P = 0.00). The differences of MCV, MCH and MCHC between the two groups were significant (all P <0.05). Among 45 IDA cases, 26 cases had HP infection, the infection rate was 57.8% (26/45). Of the 367 non-IDA cases, 101 cases had HP infection, the infection rate was 27.5% (101/367). The difference between the two was statistically significant (x2 = 17.21, P = 0.00). Conclusion: There is a significant correlation between HP infection and IDA. HP infection may be the reason of IDA.