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利用粘液组化法对282例胃癌活检标本进行分类,同时用硼酸美蓝染色法对胃癌癌旁粘膜作组织切片检测HP.结果:150例肠型胃癌中其癌旁粘膜以萎缩性炎症为主,占79.33%,HP检出率为36.67%;116例弥漫型胃癌中,癌旁以浅表性胃炎为多见(62.93%),总HP阳性率为57.75%,其中73例癌旁浅表性胃炎,69.86%见HP感染.同时发现青年组中弥漫型胃癌的发生率二倍于肠型胃癌.显示弥漫型胃癌与萎缩肠化关系不密切,HP阳性的浅表性胃炎发生弥漫型胃癌的危险性高于肠型胃癌.并讨论了HP的致癌作用.
Mucohistochemical method was used to classify 282 gastric cancer biopsy specimens. The paracancerous mucosa of gastric cancer was also detected by tissue section biopsy with HP. Results: The paraneoplastic mucosa of 150 cases of intestinal type gastric cancer was mainly atrophic inflammation. , accounting for 79.33%, HP detection rate of 36.67%; 116 cases of diffuse gastric cancer, superficial gastritis near the cancer (62.93%), the total HP positive rate was 57.75%, of which 73 cases of superficial near the cancer Gastritis, 69.86% seen HP infection. At the same time found that the incidence of diffuse gastric cancer in the young group was twice as much as intestinal type gastric cancer. Shows that diffuse gastric cancer and atrophy and intestinal metastasis are not closely related, HP-positive superficial gastritis occurs diffuse gastric cancer The risk is higher than intestinal type gastric cancer. The carcinogenic effect of HP is also discussed.