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目的观察生长抑素联合泮托拉唑治疗非静脉曲张性上消化道出血的疗效。方法将我科86例非静脉曲张性上消化道出血患者随机分为对照组和试验组。试验组44例采用生长抑素剂量(6mg/d)联合泮托拉唑进行治疗;对照组共42例,仅给予泮托拉唑进行治疗。比较两组治疗的有效率及平均住院时间。结果试验组的有效率为95.5%,优于对照组的83.3%,对照组的平均止血时间36.4±6.9h,明显长于试验组的25.8±8.4h,差异有统计学意义(P<0.05)。结论生长抑素联合泮托拉唑治疗非静脉曲张性上消化道大出血优于仅用泮托拉唑治疗,值得临床推广使用。
Objective To observe the efficacy of somatostatin combined with pantoprazole in the treatment of non-variceal upper gastrointestinal bleeding. Methods 86 cases of non-variceal upper gastrointestinal bleeding in our department were randomly divided into control group and experimental group. Forty-four patients in the experimental group were treated with somatostatin dose (6mg / d) and pantoprazole. In the control group, 42 patients were treated with only pantoprazole. Compare the two groups of treatment efficiency and average length of stay. Results The effective rate of the experimental group was 95.5%, which was better than 83.3% of the control group. The average hemostatic time of the control group was 36.4 ± 6.9 h, which was significantly longer than that of the experimental group (25.8 ± 8.4 h). The difference was statistically significant (P <0.05). Conclusion The combination of somatostatin and pantoprazole is superior to the use of pantoprazole in the treatment of non-variceal upper gastrointestinal bleeding, which is worthy of clinical promotion.