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利用高效液相色谱分离测定的方法，研究了大鼠口服利洛司酮的药代动力学。回收率＞79％．检测灵敏度为0.1μm／ml，变异系数＜5％，口服利洛司酮后吸收迅速，24h内基本消除，利洛司酮的血药浓度──时间曲线符合一室开放模型
Pharmacokinetics of oral administration of lilopristone in rats was studied by high performance liquid chromatography (HPLC). Recovery> 79%. The detection sensitivity was 0.1μm / ml, the coefficient of variation was <5%, the absorption was rapid after oral administration of lilopristin, and was basically eliminated within 24 hours. The blood concentration of lilopristone ─ ─ time curve was in accordance with the open chamber model