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目的:探讨中药消癌平(系用中药乌骨藤制成的静脉注射用针剂)经肝动脉介入治疗晚期肝癌的疗效。方法:采用Seldinger法将预成形RH导管选择性地插到肝动脉,然后根据造影后肿瘤供血情况有选择地将导管插到相应的肿瘤血管,缓慢地将消癌平针剂200～300ml注入,3～4周后重复插管治疗1次。结果:原发性肝癌和转移性肝癌患者的症状、体征的好转率分别达到86.05％和73.53％。毒副反应很少发生,仅有轻度发热、关节疼痛和消化道反应,无肝肾功能及造血功能的损伤、骨髓抑制等毒副反应。结论:消癌平是一种低毒性、有效的介入制剂,尤其适用于对晚期肝癌的治疗。
OBJECTIVE: To investigate the therapeutic effect of traditional Chinese medicine Xiaoaiping (intravenous injection made of black vine of traditional Chinese medicine) via hepatic artery interventional treatment of advanced hepatocellular carcinoma. Methods: The pre-shaped RH catheter was selectively inserted into the hepatic artery using the Seldinger method. Then the catheter was selectively inserted into the corresponding tumor vessel according to the blood supply of the tumor after the contrast, and 200 to 300 ml of the cancer injection was slowly injected. Repeat the intubation treatment 1 to 4 weeks later. Results: The improvement rates of symptoms and signs in patients with primary liver cancer and metastatic liver cancer were 86.05% and 73.53%, respectively. Toxic side effects rarely occur, only mild fever, joint pain and gastrointestinal reactions, liver and kidney function and hematopoietic damage, bone marrow suppression and other side effects. Conclusion: Xiaoaiping is a low toxicity and effective interventional agent, especially suitable for the treatment of advanced liver cancer.