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目的分析研究成年发病的烟雾病患者甲状腺功能和其临床特点。方法将本院2012年3月~2014年3月期间收治的37例烟雾病卒中患者,62例非烟雾病卒中患者和90例对照者的甲状腺功能进行比较,分析研究成年烟雾病的临床特点。结果烟雾病卒中组男13例,女24例,其比例为1:1.9,与另外两组比较,烟雾病卒中抗甲状腺微粒体抗体(anti-TPO)水平明显增高。每组间抗甲状腺蛋白抗体(anti-TG)和亚临床甲状腺疾病无明显差异。结论成年烟雾病卒中患者anti-TPO水平升高和FT3下降,且出血型较为常见,烟雾病的发病机制可能和anti-TPO有关。
Objective To analyze the thyroid function and its clinical features in adult patients with moyamoya disease. Methods The thyroid function of 37 smog patients with stroke, 62 stroke patients without smog disease and 90 controls were analyzed from March 2012 to March 2014 in our hospital. The clinical features of adult moyamoya disease were analyzed. Results There were 13 males and 24 females in the stroke group with a ratio of 1: 1.9. Compared with the other two groups, anti-thyroid microsomal antibodies (anti-TPO) levels were significantly increased in the smog sickness group. There was no significant difference in anti-TG and subclinical thyroid disease between each group. Conclusions The level of anti-TPO and FT3 are decreased in patients with adult moyamoya disease, and the hemorrhagic type is more common. The pathogenesis of moyamoya disease may be related to anti-TPO.