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（目的）观察喉癌病人手术麻醉中应用压宁定治疗高血压的效果。（方法）将择期手术病人分为高血压组（I）和非高血压组（II）。高血压组在麻醉诱导前静点压宁定（0．smg/kg）；非高血压组在氯胺酮诱导后引起血压升高，当超过21.33/12．00kPa后静点压宁定（剂量同I组）。（结果）两级静点压宁定，3分钟后血压下降显著（P＜0．05），且维持在正常范围。I组心率无明显变化（P＞0.05m），II组心率亦不降至术前水平（P＜0．05)。（结论）在喉癌手术过程中，压宁定对原发性高血压和氛胶附麻醉引起的血压升高产生有效降压作用，并能降低氯胺酮麻醉引起的心率增快。
(Objective) To observe the effect of ning ning Ding in the treatment of patients with laryngeal cancer during the operation of anesthesia. (Methods) Patients undergoing elective surgery were divided into hypertensive (I) and non-hypertensive (II) groups. Hypertension group was anesthetized before intravenous injection of nifedipine (0.smg / kg); non-Hypertension group induced by ketamine induced hypertension, when more than 21.33 / 12.00kPa nifedipine (dose with I group). (Results) The static pressure at two levels was fixed, and the blood pressure decreased significantly after 3 minutes (P <0.05), and remained within the normal range. There was no significant change in heart rate in group I (P> 0.05m), and heart rate in group II did not decrease to preoperative level (P <0.05). (Conclusions) In the course of laryngeal cancer surgery, nifedipine has an effective antihypertensive effect on the increase of blood pressure induced by anesthesia induced by essential hypertension and phlegm, and can reduce the increase of heart rate caused by ketamine anesthesia.