目前,HP与DU关系的研究为各国专家重视,对HP致DU的学说尚有争论.最近,Moshkwitz等发现消化不良病人中HP感染的季节性改变与DU发病的季节性波动高度一致,认为DU的季节性波动可用HP感染来解释.为了解此论点的可信性,我们回顾了我院临床材料,对DU病人中的HP季节性变化作一调查. At present, the study on the relationship between HP and DU has been paid much attention by experts from all over the world, and there is controversy about the theory of HP-induced DU. Recently, Moshkwitz et al found that the seasonal change of HP infection in patients with dyspepsia was highly consistent with the seasonal fluctuation of DU, Of seasonal fluctuations can be explained by HP In order to understand the credibility of this argument, we reviewed the clinical material in our hospital to investigate the seasonal changes in HP in a survey of HP patients.