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芘是多环芳烃的一个代表性化合物。预防职业性癌症将测定尿中芘的主要代谢物1-羟基芘作为接触多环芳烃的生物监测指标。对不同工作岗位的电解铝工人,同时测定个体接触多环芳烃的浓度及尿中排出1-羟基芘的浓度,发现在个体评价的基础上,1-羟基芘的水平与空气中芘的浓度、与空气中苯并(a)芘的浓度都呈显著相关,与空气中多环芳烃总浓度也呈显著相关。
Pyrene is a representative compound of PAHs. Prevention of occupational cancer The primary metabolite of pyrene in urine, 1-hydroxypyrene, was determined as a bio-monitoring indicator of PAH exposure. On the basis of individual evaluation, the level of 1-hydroxypyrene and the concentration of pyrene in the air were measured. The results showed that the concentration of 1-hydroxypyrene and the concentration of pyrene in the air, And the concentration of benzo (a) pyrene in the air were significantly correlated with the total concentration of PAHs in the air also showed a significant correlation.