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目的比较连续与间隙雾化吸入硫酸沙丁胺醇治疗中重度支气管哮喘临床疗效。方法将40例中重度支气管哮喘患者随机分为连续疗法组和间隙疗法组,比较疗效。结果治疗3d后,连续疗法组肺功能改善好于间隙疗法组(p<0.05),在治疗期间两组不良反应比较无统计学差异(p>0.05)。结论连续雾化吸入硫酸沙丁胺醇治疗中重度支气管哮喘临床疗效要优于间隙疗法,但在治疗时需密切观察患者病情,当症状表现改善后应及时改用间歇雾化吸入,以减少不良反应。
Objective To compare the clinical efficacy of inhalation of salbutamol sulphate in continuous and intermittent treatment of moderate and severe bronchial asthma. Methods Forty patients with moderate or severe bronchial asthma were randomly divided into continuous therapy group and interstitial therapy group, and the curative effect was compared. Results After 3 days of treatment, the lung function of the continuous therapy group was better than that of the gap therapy group (p <0.05). There was no significant difference in adverse reactions between the two groups during the treatment (p> 0.05). Conclusions The continuous nebulization of salbutamol sulphate for the treatment of moderate-severe bronchial asthma is better than interstitial therapy. However, the patient’s condition should be closely observed during the treatment. When the symptom is improved, intermittent inhalation should be switched to reduce the adverse reactions.