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目的探讨卵巢癌患者化疗后感染现状和影响因素。方法选取2011年1月至2013年1月收治的302例卵巢癌患者的临床资料,进行描述性统计和二分类Logistic回归分析。结果卵巢癌患者化疗后感染发生率为10.6%(32/302),以上呼吸道感染最多见(37.5%),多因素Logistic回归分析发现,高龄(OR=7.692,P=0.000)、侵入性操作多(OR=13.074,P=0.000)、白细胞数低(OR=15.864,P=0.000)和住院时间>21天(OR=10.033,P=0.000)是卵巢癌患者化疗后感染的影响因素。结论卵巢癌患者化疗后感染发生率较高,其发生受多方面因素影响。
Objective To investigate the status and influencing factors of infection in patients with ovarian cancer after chemotherapy. Methods The clinical data of 302 patients with ovarian cancer who were admitted from January 2011 to January 2013 were analyzed by descriptive statistics and Logistic regression analysis. Results The incidence of post-chemotherapy infection in ovarian cancer patients was 10.6% (32/302), with the most common respiratory infections (37.5%). Multivariate logistic regression analysis showed that older patients (OR = 7.692, P = 0.000) (OR = 13.074, P = 0.000), low leukocyte number (OR = 15.864, P = 0.000) and length of hospital stay> 21 days (OR = 10.033, P = 0.000) were the influencing factors of postoperative chemotherapy in ovarian cancer patients. Conclusion The incidence of infection in patients with ovarian cancer after chemotherapy is high, the occurrence of which is affected by many factors.