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在应用传统抗惊厥治疗无效时,利多卡因作为控制新生儿惊厥发作的一种有效药物而常使用。有关利多卡因对新生儿心率的影响和心律失常的发生尚了解不多,本研究的目的是评价心律失常发生率与新生儿惊厥发作时使用利多卡因的关系。对207例新生儿惊厥发作使用利多卡因治疗的病例资料进行了回顾分析,这些新生儿均在惊厥发作10min内被给予了2mg/kg的负荷
Lidocaine is often used as a potent drug to control seizures in newborns when traditional anticonvulsant therapy is not effective. The effect of lidocaine on neonatal heart rate and arrhythmia is not much understood. The purpose of this study was to evaluate the association between the incidence of arrhythmia and the use of lidocaine in neonatal seizures. A retrospective analysis of 207 cases of neonatal seizures treated with lidocaine was conducted. All these newborns were given a 2 mg / kg load within 10 min of seizures