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目的探讨比索洛尔与卡维地洛对心衰患者心律失常的作用。方法对40例慢性心衰患者随机分组进行比索洛尔和卡维地洛治疗,渐增至最大耐受剂量后观察16周,治疗前后行24h动态心电图检查进行对比,分析心律失常的变化情况。结果治疗后两组的心律失常均有一定改善,卡维地洛组更明显,对室性期前收缩的治疗效果显著,比索洛尔对房性期前收缩的治疗未显效。但治疗效果及两组间差异均无统计学意义。结论卡维地洛对心力衰竭患者心律失常的治疗效果较比索洛尔略高。
Objective To explore the effect of bisoprolol and carvedilol on arrhythmia in patients with heart failure. Methods Forty patients with chronic heart failure were randomly divided into two groups: bisoprolol and carvedilol. The maximum tolerated dose was gradually increased to 16 weeks. Before and after treatment, 24h dynamic electrocardiogram was used to compare and analyze the change of arrhythmia. Results After treatment, arrhythmia was improved in both groups. The carvedilol group was more obvious, and the treatment effect on ventricular premature contraction was significant. Bisoprolol was not effective in the treatment of atrial premature contractions. However, the treatment effect and no significant difference between the two groups. Conclusion Carvedilol treatment of heart failure patients with arrhythmia slightly higher than bisoprolol.