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细粒棘球绦虫病(CE)是一种由细粒棘球绦虫幼虫感染而流行的蠕虫病,广泛感染人及牲畜。宿主和虫体关系的主要特征是慢性感染的同时可检测到抗虫体的体液免疫和细胞免疫。虫体之所以能在宿主体内存活有赖于有效的免疫逃避机制。棘球蚴的囊液中有两种抗原的含量比较丰富,即抗原5和抗原B,其中后者占囊液总内容物的10％,是一个160 kDa的热稳定脂蛋白,经SDS-PAGE后分成3个亚单位——8或12,16,20或24kDa。
Echinococcus granulosus (CE) is a worm disease that is endemic to larvae of Echinococcus granulosus and infects humans and livestock extensively. The main characteristic of the relationship between the host and the parasites is the humoral and cellular immunity of the insect-resistant body can be detected simultaneously with the chronic infection. The reason why parasites survive in the host depends on an effective immune evasion mechanism. Echinococcosis fluid in the cytoplasm of the two antigens rich, namely antigen 5 and antigen B, which accounted for 10% of the total contents of cystic fluid, is a 160 kDa thermostable lipoprotein, SDS-PAGE Divided into 3 subunits - 8 or 12, 16, 20 or 24kDa.