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目的探讨高血压颈动脉斑块与缺血性脑卒中患病率之间的相关性。方法入选原发性高血压患者120例,以是否伴有缺血性脑卒中分为两组,伴缺血性脑卒中者75例,单纯高血压组45例,彩色多普勒超声检查两组患者的颈动脉斑块的数量、部位、大小和颈总动脉内中膜厚度。结果缺血性脑卒中组与单纯高血压组比较,颈动脉斑块的发生率明显增加(74.67%vs 53.33%,P<0.05),不稳定斑块的比例较高(66.67%vs 31.11%,P<0.05),斑块的部位、大小及颈总动脉内中膜厚度两组无差异(P>0.05),多因素回归分析显示,年龄、糖尿病是颈动脉斑块形成的独立危险因素,颈动脉斑块可增加高血压患者缺血性脑卒中的风险。结论颈动脉斑块与高血压缺血性脑卒中的发生密切相关,是缺血性脑卒中的独立危险因素。
Objective To investigate the correlation between hypertension carotid plaque and the prevalence of ischemic stroke. Methods A total of 120 patients with essential hypertension were enrolled in this study. The patients with ischemic stroke were divided into two groups: 75 cases with ischemic stroke, 45 cases with simple hypertension and 25 cases with color Doppler ultrasonography The number, location, size and carotid intima-media thickness of patients with carotid plaques. Results The incidence of carotid plaque was significantly increased in ischemic stroke group compared with those in simple hypertension group (74.67% vs 53.33%, P <0.05), and the proportion of unstable plaque was higher (66.67% vs 31.11% P <0.05). There were no significant differences in the location and size of carotid artery and intima-media thickness (P> 0.05). Multivariate regression analysis showed that age and diabetes were independent risk factors for carotid plaque formation Arterial plaques increase the risk of ischemic stroke in hypertensive patients. Conclusion Carotid artery plaque is closely related to the occurrence of ischemic stroke and is an independent risk factor for ischemic stroke.