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为了解临床医护人员的血清HP抗体阳性率;了解人群中HP感染率,探讨幽门螺杆菌感染的传播途径。对200名临床医护人员,145例非临床医务人员及201例消化科病人共546例应用酶联法测定血清HP抗体。结果发现临床医护人更血清HP抗体阳性率高于非临床医务人员血清HP抗体阳性率,几乎接近于消化科住院病人血清HP抗体阳性卑,有消化不良症状者的血清HP抗体阳性率高于无消化不良症状者血清HP抗体阳性率,有消化性溃疡家族密切接触史者成员的血清HP抗体阳性率高于无消化性溃疡家族史者的血清HP抗体阳性率。(1)临床医护人员与病人密切接触是易受HP感染的高危人群,提示HP通过口—口或粪——口途径传播。(2)HP感染与症状有关。(3)HP可能在家庭中或配偶间交叉感染或两者来自同一感染。
In order to understand the positive rate of serum HP antibody in clinic staff, to understand the prevalence of HP in the population and to explore the route of transmission of Helicobacter pylori infection. A total of 546 cases of 200 clinical medical staff, 145 non-clinical medical staff and 201 cases of gastrointestinal diseases were assayed for serum HP antibody by ELISA. The results showed that the positive rate of serum HP antibody in clinical caregivers was higher than that of non-clinician serum HP antibody, which was close to that of inpatients with Gastroenterology. The positive rate of serum HP antibody was higher in patients with dyspepsia The positive rate of serum HP antibody in dyspeptic symptoms and the positive rate of serum HP antibody in those with close history of peptic ulcer family were higher than the positive rate of serum HP antibody in those without family history of peptic ulcer. (1) Clinicians in close contact with patients are at high risk for HP infection, suggesting that HP is transmitted through the mouth-mouth or fecal-oral route. (2) HP infection and symptoms. (3) HP may cross-infection in the home or spouse or both from the same infection.