论文部分内容阅读
目的 观察足月胎膜早破孕妇阴道内放置小剂量米索前列醇 (米索 )引产的有效性和安全性。方法 72例足月胎膜早破的孕妇随机分成二组 ,米索组 (n =30 )在孕妇的后穹窿单次放置 5 0 μg米索 ,对照组 (n =42 )用催产素静滴引产。结果 米索组用药后 5小时内正规宫缩发动者 2 4例 (占 80 % ) ,较催产素组 ( 7例 )差异有显著性 (P <0 .0 1) ;米索组阴道分娩总产程 ( 482± 199min)较催产素组 ( 6 2 9±2 34min)短 (t=2 .44 ,P <0 .0 5 ) ;剖宫产率 ( 2 0 % )较催产素组 ( 48% )低 (P <0 .0 5 ) ;子宫强直性收缩的发生率 ( 6 .7% )较催产素组 ( 16 .7% ) (P <0 .0 5 )。结论 阴道后穹窿放置小剂量米索对于足月胎膜早破病人的引产是有效和安全的
Objective To observe the effectiveness and safety of low-dose misoprostol (misoprostol) in vaginal delivery of full-term premature rupture of membranes. Methods Seventy-two pregnant women with full-term premature rupture of membranes were randomly divided into two groups. Misoprostol (n = 30) received 50 μg of misoprostol in posterior fornix and control group (n = 42) Induction. Results The misoprostol group had 24 cases (80%) of normal contractions within 5 hours after drug administration, which was significantly different from that of oxytocin group (7 cases) (P <0.01). The total vaginal delivery (482 ± 199 min) was shorter than that of oxytocin (62 9 ± 2 34 min) (t = 2.44, P <0.05); cesarean section rate (20% ) (P <0.05). The incidence of tonic contractions in uterus (6.7%) was significantly higher than that in oxytocin group (16.7%) (P <0.05). Conclusion Posterior vaginal fornix placement of low dose misoprostol is effective and safe for induction of labor in term premature rupture of membranes