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纤维结合蛋白(Fibronectin)为一组高分子糖蛋白。最初在血浆的冷不溶性组份中发现(组份Ⅰ-1),这一组份的主要成分为纤维蛋白原,但这种新发现的血浆成分的沉降系数较大,向阳极的电泳速度较快且不被凝血酶所凝结。以后曾被命名为可溶性原纤维细胞抗原、大的外部转化蛋白、细胞表面蛋白、细胞粘附因子、冷不溶性蛋白、调理素蛋白、细胞扩散因子及抗明胶因子等。近年来根据其与纤维类蛋白结合的能力才统一命名为纤维结合蛋白(fn)。由于纤维结合蛋白与细胞形态
Fibronectin is a group of high molecular glycoproteins. Initially found in the cold insoluble fraction of plasma (component I-1), the main constituent of this component is fibrinogen, but the sedimentation coefficient of this newly discovered plasma component is greater and the rate of electrophoresis towards the anode is faster Fast and not coagulated by thrombin. Later been named soluble fibroblast antigens, large external transformation protein, cell surface protein, cell adhesion factor, cold insoluble protein, opsonin, cell proliferation factor and antigelatin factor and so on. In recent years, according to its ability to bind with fibronectin was unified named fibronectin (fn). Due to fibronectin and cell morphology