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目的 了解影响苯丙胺类物质(ATS)使用者发生高危性行为的相关因素,为制订干预措施提供相关理论依据.方法 于2013年8月-2014年12月,以来自上海市强制隔离戒毒所的1 677名ATS依赖者为研究对象,以既往1年有≥2个性伙伴,并在最近1个月的性行为中从未使用过安全套为分组标准,满足上述条件为高危性行为组(697名),不满足条件为非高危性行为组(980名),比较两组在人口学资料、药物滥用史、以及B arratt冲动性量表(BIS-Ⅱ)得分上的差异,并对两组之间有差异的变量进行logistic逐步回归分析.结果 男性(OR=1.934,95％CI=1.484 ～2.521)、合并多药滥用(OR=1.773,95％CI=1.302 ～2.414)、初次性行为年龄较早(OR=1.791,95％CI=1.426～2.250)、使用ATS时间越长(OR=1.478,95％CI=1.197 ～ 1.826)、冲动得分高(OR=1.382,95％ CI=1.120～1.707)的ATS使用者可能更容易出现高危性行为.结论 ATS患者高危性行为影响因素较为复杂,应根据相应特点采取针对性的干预措施,以减少或控制高危性行为.“,”Objective To explore related factors of high risk sexual behaviors among amphetamine-type stimulant (ATS) addicts and to provide evidences for future intervention.Methods Totally 1 677 ATS addicts in Shanghai Compulsory Isolated Detoxification Center were recruited and divided into a high risk group (697 with two or more sexual partners during recent one year and never using condom in sexual activity during recent one month)and a non-risk group (980);all the participants were surveyed with a questionnaire on demographic characteristics and drug use history and Barratt Impulsiveness Scale (BIS-Ⅱ) between August 2013 and December 2014.Logistic regression analysis was used to assess discrepant variables between the two groups.Results The participants being male gender (odds ratio [OR] =1.934,95 ％ confidence interval [CI]:1.484-2.521),with multiple drug use (OR =1.773,95 ％ CI:1.302-2.414),having first sexual behavior at early age (OR =1.791,95 ％ CI:1.426-2.250),with long-term ATS use (OR =1.478,95％ CI:1.197-2.826),and with a high impulsivity score (OR =1.382,95％ CI:1.120-2.707) were more likely to have high risk sexual activity.Conclusion The influence factors of high-risk sexual behavior are relatively complex among amphetamine-type stimulant addicts,suggesting specific intervention strategies should be developed to reduce highrisk sexual activities among the population.