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目的探讨复方醋酸棉酚联合米非司酮治疗子宫肌瘤的临床疗效。方法选取2010年4月至2012年4月我院收治的105例子宫肌瘤患者,根据临床治疗方法的不同,将其分为对照A组、对照B组和联合组。对照A组35例患者给予复方醋酸棉酚治疗,对照组B组35例患者给予米非司酮治疗,联合组35例患者给予复方醋酸棉酚联合米非司酮治疗,对比三组患者临床治疗效果。结果与对照A组和对照B组患者相比,联合组治疗后子宫肌瘤体积有明显变化,且联合组患者临床总有效率明显优于对照A组和对照B组。三组患者对比差异明显,具有统计学意义(P<0.05)。结论复发醋酸棉酚联合米非司酮治疗子宫肌瘤临床治疗效果明显优于单纯使用复方醋酸棉酚或米非司酮,值得临床推广和应用。
Objective To investigate the clinical efficacy of compound gossypol acetate combined with mifepristone in the treatment of uterine fibroids. Methods From April 2010 to April 2012, 105 cases of uterine fibroids admitted to our hospital were divided into control group A, control group B and combination group according to the different clinical treatment methods. 35 patients in control group A received compound gossypol acetate, 35 patients in control group B received mifepristone, and 35 patients in combination group received compound gossypol acetate and mifepristone, compared with three groups of patients with clinical treatment effect. Results Compared with control group A and control group B, the volume of uterine fibroids in the combination group changed significantly, and the total effective rate in the combination group was significantly better than that in the control group A and the control group B. The differences between the three groups were significant and statistically significant (P <0.05). Conclusions The clinical efficacy of recurrent gossypol combined with mifepristone in the treatment of uterine fibroids is superior to that of compound gossypol acetate or mifepristone alone. It is worthy of clinical promotion and application.