报道一例新生儿MN溶血病，该患儿出生24小时内出现黄疸，逐渐加重，血清胆红素峰值高达294.3μmol/L，并出现重度贫血，血红蛋白低至68g/L，予静脉注射丙种球蛋白输注及光疗退黄、输血、口服苯巴比妥退黄等综合治疗后，患儿病情好转，痊愈出院，出生1月时因贫血输血一次，后随访生长发育良好。“,” reported a case of a newborn MN hemolysis disease, the child was born 24 hours to appear icteric, gradualy increased, serum bilrubin peak as high as 294.3 (including mol/L, and severe anemia and hemoglobin as low as 68 g/L, to intravenous infusion of ivig and phototherapy retreat yelow, transfusion and oral phenobarbital retreat yelow after comprehensive treatment, patients get better and recover from hospital, was born in January due to anemia, a blood transfusion, folow-up after good growth and development.