作者1984年6月至1985年7月对团居人口中年龄为67、72,77、82和87岁的488人,调查和随访了398人。经核对用药情况,发现21人使用过氟苯桂嗪(flunarizine,冠脉扩张药),其中2例有老年性痴呆,9例(氟苯桂嗪的每天剂量为:7例10毫克,2例20毫克)有中～重度抑郁症,7例表现为酷似帕金森病的运动徐缓,但无1例有强直性或静息性震颤。这些有抑郁和运动徐缓的病人停用氟苯桂嗪后,4例用阿 From June 1984 to July 1985, a total of 488 persons aged 67, 72, 77, 82 and 87 years from the group were surveyed and followed up 398 people. After checking the medication situation, we found that 21 people used flunarizine (coronary artery dilation), including 2 cases of senile dementia, 9 cases (fluorouracil daily dose: 7 cases of 10 mg, 2 cases 20 mg) had moderate-to-severe depression and 7 showed bradykinesia similar to Parkinson’s disease, but none had tonic or resting tremor. Of these patients who had depressive and bradykinesia, they discontinued use of flubenzuril