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口服避孕药(OC)的应用,有发生各种心血管疾病的危险性,包括卒中与心肌梗塞。也可增高血压。1974年Weir作前瞻性调查,应用OC比不用OC的妇女,血压增高的发病率约多1.5～3倍,而用宫内节育器或隔膜避孕的妇女,血压却轻度下降。一般白人较黑人用OC后血压升高者多见,可能是普通居民群体内,黑人的平均血压略高于白人,因而掩盖了升高血压的作用。我国只有复方炔雌醚用药6个月后,引起血压增高者占41.6%的报导。几乎所有OC与高血压关系的研究,均来自发达国家,大多数属于横向的现况调查,而纵向的回顾与前瞻性调查较少,如Walnut Creek OC
The use of oral contraceptives (OCs) is associated with the risk of developing various cardiovascular diseases, including stroke and myocardial infarction. Can also increase blood pressure. In a prospective survey by Weir in 1974, the prevalence of BP was approximately 1.5 to 3 times higher in women who used OC than in women who did not use OC, whereas women with IUD or diaphragm contraception had a slightly lower blood pressure. It is more common in whites than in blacks with elevated blood pressure after OC. It may be that in the general population, the mean blood pressure of blacks is slightly higher than that of whites, thus obscuring the effect of raising blood pressure. China only compound ethinyl estrus medication after 6 months, caused by high blood pressure accounted for 41.6% of the reports. Almost all of the studies on the relationship between OC and hypertension were from developed countries, most of which were horizontal state-of-affairs surveys while less longitudinal and prospective ones such as Walnut Creek OC