目的探讨下丘脑错构瘤的显微手术入路。方法回顾性总结4例下丘脑错构瘤的临床资料,均行显微手术,翼点入路1例,翼点联合颞下入路3例。结果 4例下丘脑错构瘤病例全切除3例,1例次全切,手术效果良好。结论翼点及颞下联合入路切除巨大下丘脑错构瘤是一种较好的手术方法。 Objective To investigate the microsurgical approach of hypothalamic hamartoma. Methods The clinical data of 4 patients with hypothalamic hamartoma were retrospectively reviewed. Microsurgery was performed in all cases. One patient had pterional approach and three had wing approach combined with infratemporal approach. Results 4 cases of hypothalamic hamartoma cases of total resection in 3 cases, 1 case subtotal resection, the effect is good. Conclusions Wing point and infratemporal approach to the removal of huge hypothalamic hamartoma is a good surgical method.