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目的比较局部性肾癌采用肾癌根治术与保留肾单位手术的效果。方法将我院2009年1月-2012年12月局限性肾癌患者80例随机分为两组各40例,对照组采用传统肾癌根治术治疗,观察组采用保留肾单位手术治疗,回顾两组临床资料。结果观察组各项手术操作及住院时间、术中出血量高于对照组(P<0.05);术后1个月及1年随访观察组血清肌酐明显低于对照组(P<0.05)。两组并发症率、远期复发率及转移率无明显差异(P>0.05)。结论局限性肾癌采用保留肾单位手术治疗,可较好保护肾功能,提高患者生存质量。
Objective To compare the effects of radical nephrectomy and nephron surgery in locally advanced renal cell carcinoma. Methods 80 patients with localized renal cell carcinoma in our hospital from January 2009 to December 2012 were randomly divided into two groups of 40 cases. The control group was treated with conventional radical nephrectomy. The observation group was treated with retained nephron. Group clinical data. Results The operation time, hospitalization time and blood loss in observation group were higher than those in control group (P <0.05). Serum creatinine in observation group was significantly lower than that in control group at 1 month and 1 year after operation (P <0.05). Complications rates, long-term recurrence rates and metastasis rates had no significant difference between the two groups (P> 0.05). Conclusion The limited renal cell carcinoma with retained nephron surgical treatment, can better protect renal function, improve patient quality of life.