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20例口服一年以上茶碱的哮喘患者为A组,B组为10例用其它药物治疗的哮喘患者,C组为不用药的健康对照组。A组与B、C两组进行比较研究。发现A组哮喘患者T抑制细胞(Ts)数目增多,A组患者Ts占T细胞总数的37±7％,B组Ts占T细胞总数的19±4％(P<0.01),C组Ts占T细胞总数的26±6％(P<0.01),而T细胞总数无差异。另发现移植物抗宿主反应(GVHR)减弱,A组20例患者中17例GVHR阴性,阴性率达85％,而B、C两组,除一例为阴
Twenty patients with asthma who took more than one year of theophylline were group A, 10 patients with asthma were treated with other drugs in group B, and healthy control group without medication. A group and B, C two groups for comparative study. It was found that the number of T suppressor cells (Ts) increased in group A asthmatic patients, the number of T cells in group A was 37 ± 7%, the number of T cells in group B was 19 ± 4% (P <0.01) T cells 26 ± 6% (P <0.01), while the total number of T cells was no difference. Another found that graft-versus-host response (GVHR) weakened, A group of 20 patients, 17 cases of GVHR negative, the negative rate of 85%, while B, C two groups, except for one case of Yin