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目的:研究糖化血红蛋白(HbAlc)、超敏C反应蛋白(hs-CRP)、微量尿清蛋白(mALB)与糖尿病合并冠心病(CHD)的关系。方法:将2型糖尿病(T2DM)患者108例分为糖尿病合并冠心病组(观察组)和糖尿病非合并冠心病组(对照组)。测定收缩压(SBP)、舒张压(DBP)、身高、体重、三酰甘油(TG)、总胆固醇(TC)、高密度脂蛋白(HDL-C)、低密度脂蛋白(LDL-C)、空腹血糖(FPG)和HbAlc、hs-CRP、mALB,并计算体重指数(BMI)。结果:观察组血压、TC、LDL-C、BMI、FPG、HbA1c、mALB、hs-CRP均显著高于对照组(P<0.05,P<0.01),HDL-C显著低于对照组(P<0.01)。结论:HbAlc等可作为筛查和监测糖尿病合并冠心病早期发生和发展的指标。
Objective: To study the relationship between HbAlc, hs-CRP, mALB and diabetes with coronary heart disease (CHD). Methods: One hundred and eighty patients with type 2 diabetes mellitus (T2DM) were divided into two groups: diabetes mellitus with coronary heart disease (observation group) and diabetes mellitus without coronary heart disease (control group). SBP, DBP, body weight, triglyceride (TG), total cholesterol (TC), high density lipoprotein (HDL-C), low density lipoprotein (LDL- Fasting plasma glucose (FPG) and HbAlc, hs-CRP, mALB, and body mass index (BMI) were calculated. Results: The blood pressure, TC, LDL-C, BMI, FPG, HbA1c, mALB and hs-CRP in the observation group were significantly higher than those in the control group (P < 0.01). Conclusion: HbA1c can be used as an index to screen and monitor the early occurrence and development of diabetes complicated with coronary heart disease.