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目的通过观察血小板参数在正常晚期妊娠妇女和妊高征患者的变化,探讨其临床意义。方法采用国产迈瑞BC5800全自动血细胞分析仪分别对正常晚期妊娠妇女(70例),妊高征患者(70例),对照组(正常体检妇女70例)血液标本进行血细胞分析,着重观察血小板计数(PLT),血小板平均体积(MPV)、血小板分布宽度(PDW)、血小板压积(PCT)测定的结果,并比较各组间的差异。结果妊高征组和正常孕妇组的MPV、PDW显著高于对照组(P<0.01);妊高征组MPV、PDW明显高于正常孕妇组(P<0.05);妊高征组的PLT、PCT显著低于对照组(P<0.01)。结论妊高征患者由于血小板消耗和破坏增加,导致血小板减少,MPV、PDW明显增高,因此,检测血小板参数对预测妊高征的发生有一定参考意义。
Objective To investigate the clinical significance of platelet parameters in patients with normal late pregnancy and pregnancy induced hypertension (PIH). Methods The blood samples of 70 normal pregnant women, 70 pregnant women with PIH and 70 healthy pregnant women were included in this study. Blood samples were obtained from blood samples collected from domestic pregnant women with BC5800 automatic hematology analyzer. The platelet count PLT, mean platelet volume (MPV), platelet distribution width (PDW) and platelet pressure (PCT) were measured. The differences between groups were also compared. Results The MPV and PDW in PIH group and normal pregnant women group were significantly higher than those in control group (P <0.01). The MPV and PDW in PIH group were significantly higher than those in normal pregnant women group (P <0.05) PCT was significantly lower than the control group (P <0.01). Conclusions Patients with PIH have increased thrombocytopenia and decreased thrombocytopenia. MPV and PDW are significantly increased. Therefore, the detection of platelet parameters has some reference value for predicting the occurrence of PIH.