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为了研究胆红素对急性运动所致氧化应激的保护作用，将Ｗｉｓｔａｒ大鼠随机分为对照组、运动组、运动恢复组、胆红素处理运动组、胆红素处理运动恢复组，共５组，分别灌胃生理浓度的胆红素或生理盐水４周，负重（体重的５％）游泳２小时后处死，测定有关的指标。结果表明，生理浓度的胆红素能抑制运动后血清和用）肠肌匀浆丙二醛（ＭＤＡ）含量的升高，抑制运动后超氧化物歧化酶（ＳＯＤ）活性的下降，同时也可以减少运动后氧自由基的产生并降低体内自发产生的氧自由基，提示胆红素具有一定的抗运动所致氧化应激的作用。
In order to study the protective effects of bilirubin on acute exercise-induced oxidative stress, Wistar rats were randomly divided into control group, exercise group, exercise recovery group, bilirubin-treated exercise group, bilirubin-treated exercise recovery group The rats in each group were given 5 mg bilirubin or normal physiological saline for 4 weeks. The rats were sacrificed after 2 hours’ swimming (5% of body weight), and the indexes were determined. The results showed that the physiological concentration of bilirubin can inhibit the serum and exercise after exercise) the increase of intestinal malondialdehyde (MDA) content, inhibition of exercise decreased superoxide dismutase (SOD) activity, but also can Reduce the generation of oxygen free radicals after exercise and reduce the spontaneous generation of oxygen free radicals in the body, suggesting that bilirubin has some anti-exercise-induced oxidative stress.