t(8;21)易位约见于30％～40％的伴有成熟的急性髓细胞白血病(AML-M2)。伴有该易位的AML-M2患者通常预后较佳。为了寻找有助于区分t(8;21)~+AMLM2与t(8;21)~-AML-M2的形态学特征,作者对30例t(8;21)~+AML-M2和50例t(8;21)~-AML-M2患者的骨髓细胞形态学和细胞化学特征作了深入细致的分析比较。 方法 骨髓涂片采用常规的May-Gronwald-Giemsa染色和髓过氧化物酶(MPO)染色。由3例预先不知道患者染色体检查结果并且富有经验的血液学工 The t(8;21) translocation was found in 30% to 40% of mature acute myeloid leukemia (AML-M2). AML-M2 patients with this translocation usually have a better prognosis. In order to find out the morphological characteristics of t(8;21)~+AMLM2 and t(8;21)~-AML-M2, the authors studied 30 cases of t(8;21)~+AML-M2 and 50 cases. The morphological and cytochemical features of bone marrow cells in t(8;21)~-AML-M2 patients were analyzed in detail. Methods Bone marrow smears were stained with conventional May-Gronwald-Giemsa staining and myeloperoxidase (MPO) staining. 3 experienced haematologists who had no prior knowledge of the patient’s chromosome test results