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我科于2000年3月～2000年6月先后收治进食生鱼胆导致急性肾功能衰竭和不同程度肝损害、心肌损害病人3例。经对症及血液透析治疗后痊愈,现报告如下。资料与方法一、一般资料:3例患者中男性1例,女性2例。年龄32～50岁,平均41岁。进食淡水生鱼胆2～4个,发病时间为0.5～4小时,首诊时间12小时～7天。二、临床表现:首发症状均为恶心、呕吐、腹痛、腹泻等消化系统症状,少尿2例,无尿1例。无尿出现在进食生鱼胆后的2～4天;3例病人出现黄疸,其中1例病人出现窦性心动过缓。三、实验室资料:血 WBC 均大于1.0×10~9/L,尿蛋白++-+,尿镜检:WBC 5～10个/HP,RBC 3～8个/HP,均有管型尿。3例患者肾功能、肝功能、心肌酶学均有变化,见表1。
My department in March 2000 ~ June 2000 has admitted to eat raw fish gallbladder lead to acute renal failure and varying degrees of liver damage, myocardial damage in 3 patients. After symptomatic and hemodialysis healed, are as follows. Materials and Methods First, the general information: 1 patient in 3 patients, 2 females. Age 32 to 50 years old, average 41 years old. Eat freshwater fish 2 to 4, the onset time of 0.5 to 4 hours, the first consultation time of 12 hours to 7 days. Second, the clinical manifestations: The first symptoms are nausea, vomiting, abdominal pain, diarrhea and other digestive symptoms, oliguria in 2 cases, anuria in 1 case. Anuria appeared 2 to 4 days after eating raw fish bile; 3 patients had jaundice, of which 1 patient had sinus bradycardia. Third, laboratory data: blood WBC were greater than 1.0 × 10 ~ 9 / L, urinary protein ++ - +, urinalysis: WBC 5 ~ 10 / HP, RBC 3 ~ 8 / HP, are tubular urine . 3 patients with renal function, liver function, myocardial enzymes have changed, Table 1.