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目的研究血液病房真菌感染与消毒管理对策。方法采取回顾性调查方法,对某医院血液病房住院患者真菌感染现状进行调查,制定消毒防护措施。结果共调查某医院血液病房765例恶性血液病患者,发生侵袭性真菌感染患者78例,感染率为10.20%。从患者送检标本中检出真菌61株,白色念珠菌占49.18%,热带念珠菌占13.11%,曲霉菌占9.84%。感染部位主要为呼吸道,构成比为57.69%,其次是口腔感染。结论血液病房患者侵袭性真菌感染发病率高,病原菌主要来源于患者内源性感染灶及交叉感染,加强消毒隔离是重点防控对策。
Objective To study the fungal infection and disinfection management in blood wards. Methods A retrospective survey was conducted to investigate the prevalence of fungal infection in inpatients in a blood ward of a hospital and to develop disinfection and protection measures. Results A total of 765 patients with hematological malignancies were investigated in a blood bank of a hospital. There were 78 patients with invasive fungal infection, the infection rate was 10.20%. 61 strains of fungi were detected from the specimens tested by the patients, Candida albicans accounted for 49.18%, Candida tropicalis 13.11% and Aspergillus accounted for 9.84%. Infections were mainly respiratory, with a ratio of 57.69%, followed by oral infections. Conclusion The prevalence of invasive fungal infection in blood ward patients is high. The pathogen mainly comes from endogenous infection and cross-infection in patients. Strengthening disinfection and isolation is the key control strategy.