莫西沙星最重要的微生物学性质之一是对需氧革兰氏阳性球菌显示出高体外活性 ,一般比环丙沙星强4～ 8倍 ,与其 C7-位的氮杂双环有关。对甲氧西林敏感的金黄色葡萄球菌和表皮葡萄球菌对莫西沙星敏感(MIC≤ 2 mg/ L ) ,对甲氧西林耐药的金黄色葡萄球菌和表皮葡萄球菌对莫西沙星的 One of the most important microbiological properties of moxifloxacin is its high in vitro activity against aerobic gram-positive cocci, generally 4 to 8 times stronger than ciprofloxacin, related to its azacitidine at the C7-position. Methicillin-sensitive Staphylococcus aureus and Staphylococcus epidermidis were sensitive to moxifloxacin (MIC <2 mg / L), to methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis against moxifloxacin