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目的探讨阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者阻塞点截面积与其发病危险因素、睡眠呼吸参数的相关性。方法应用多层螺旋CT测量2007年1月至2008年3月新疆医科大学第一附属医院呼吸内科连续收治的126例经多导睡眠监测确诊的OSAHS患者阻塞点的截面积,统计患者的身高、体重、颈围、睡眠呼吸参数、计算其体重指数(BMI),将以上各因素进行相关性分析。结果OSAHS患者的阻塞点主要发生在口咽部;阻塞点截面积与BMI、颈围呈负相关性(P<0.05),但相关性系数较小;阻塞点截面积、BMI、颈围均与病情分级指标有相关性(P<0.05),但睡眠呼吸参数与阻塞点截面积的相关性显著强于与颈围、BMI的相关性。结论阻塞点截面积是判断OSAHS病情程度的一个更加敏感、更加理想的评价指标。
Objective To investigate the relationship between the obstructive point of obstructive sleep apnea-hypopnea syndrome (OSAHS) and its risk factors and sleep breathing parameters. Methods Using multislice spiral CT to measure the cross-sectional area of obstructive points of OSAHS patients diagnosed by polysomnography in 126 consecutive patients admitted to the First Affiliated Hospital of Xinjiang Medical University from January 2007 to March 2008. The height, Body weight, neck circumference, sleep breathing parameters, calculate their body mass index (BMI), the above factors were analyzed. Results The occlusion point of OSAHS mainly occurred in the oropharynx. The cross-sectional area of obstruction was negatively correlated with BMI and neck circumference (P <0.05), but the correlation coefficient was small. The cross-sectional area of obstruction, BMI, (P <0.05). However, the correlation between sleep breathing parameters and the cross-sectional area of obstruction was significantly stronger than that of neck circumference and BMI. Conclusion Obstructive point cross-sectional area is a more sensitive and more ideal evaluation index to judge the severity of OSAHS.