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目的应用定量组织速度成像(QTVI)测定二尖瓣环运动速度评价尿毒症病患者左室舒张功能。方法应用定量组织速度成像测定30例正常人和32例尿毒症患者的二尖瓣环舒张早期峰值速度(Ve)、左房收缩期峰值速度(Va),计算Ve/Va比值;并用脉冲多普勒测定二尖瓣口舒张早期峰值血流速度E峰、舒张晚期峰值血流速度A峰,计算E/A值。结果正常组舒张早期峰值速度(E)>左房收缩期峰值速度(A),E/A>1;二尖瓣环舒张早期峰值速度(Ve)>左房收缩期峰值速度(Va),Ve/Va>1,正常组与尿毒症患者组二尖瓣口血流频谱及二尖瓣环运动组织速度成像测值有显著性差异,尿毒症患者组中二尖瓣环运动速度Ve/Va与二尖瓣血流频谱V/A无显著性差异。但在检出病例数中QTVI阳性例数明显高于血流频谱。结论应用定量组织速度成像测定二尖瓣口运动速度能较准确估计尿毒症患者左室舒张功能。
Objective To evaluate left ventricular diastolic function in patients with uremia by quantitative tissue velocity imaging (QTVI). Methods The early diastolic peak velocity (Ve) and the peak systolic velocity (Va) of mitral annulus in 30 normal subjects and 32 uremic patients were measured by quantitative tissue velocity imaging, and the Ve / Va ratio was calculated. The mitral valve early mitral diastolic peak flow velocity E peak, diastolic peak flow velocity A peak, calculated E / A value. Results The peak early diastolic velocity (E)> peak systolic velocity (A), E / A> 1 in mitral annulus, Ve> / Va> 1, there was a significant difference between the normal group and uremia patients in mitral valve flow spectrum and mitral annulus tissue velocity imaging. The mitral annulus velocity Ve / Va and Mitral flow spectrum V / A no significant difference. However, the number of positive cases of QTVI in the detected cases was significantly higher than the blood flow spectrum. Conclusions Using quantitative tissue velocity imaging to measure mitral valve velocity can accurately estimate left ventricular diastolic function in patients with uremia.