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硝基油酸是一种一氧化氮衍生的脂肪酸,有生物学活性,在体内具有相关的血管保护作用。硝基油酸通过它的强亲电子特性而发挥细胞信号转导作用,并在血管系统中介导多种细胞反应。本实验旨在研究硝基油酸在血管紧张素Ⅱ(angiotensinⅡ,AngⅡ)诱导的高血压中的保护性效应。方法和结
Nitro-oleic acid is a nitric oxide-derived fatty acid that is biologically active and has a vascular protective effect in the body. Nitro-oleic acid exerts cellular signal transduction through its strong electrophilic properties and mediates a variety of cellular responses in the vascular system. The purpose of this study was to investigate the protective effect of nitrooleic acid on hypertension induced by angiotensin Ⅱ (AngⅡ). Method and Results