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本文主要叙述金黄色葡萄球菌的致病作用,毒素在中毒性休克综合征中的作用以及凝固酶阴性葡萄球菌与临床疾病的关系。近几年来,美国报道一些与妇女月经期密切相关的疾病,主要症状为高热,全身红肿、结膜充血、腹泻、低血压及肾功能衰竭。据Wisconsin报告的37例TSS患者,均为女性,35例在月经期发病,其中23例进行宫颈或阴道分泌物分离培养,18例检出金黄色葡萄球菌。美国亚特兰大疾病控制中心报告941例确诊为TSS患者,928例为女性(99%),其中905例(98%)在月经期发病,11例在产后发病。73例死亡(7.8%)。 Bergdoll等从确诊为TSS患者中分离的65株金黄色葡萄球菌中,发现有61株(94%)
This article describes the pathogenic role of Staphylococcus aureus, the role of toxins in toxic shock syndrome, and coagulase-negative staphylococci and clinical disease. In recent years, the United States has reported some diseases closely related to women’s menstrual periods. The main symptoms are fever, generalized swelling, conjunctival hyperemia, diarrhea, hypotension and renal failure. According to Wisconsin report of 37 cases of TSS patients, all women, 35 cases of onset in the menstrual period, of which 23 cases of cervical or vaginal secretions were isolated and cultured, 18 cases of Staphylococcus aureus detected. The United States Atlanta Centers for Disease Control reported 941 cases of TSS patients diagnosed, 928 were female (99%), of which 905 (98%) onset in the menstrual period, 11 cases postpartum morbidity. 73 died (7.8%). Of the 65 Staphylococcus aureus isolates isolated from patients diagnosed with TSS, Bergdoll et al. Found 61 (94%)