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报道了４个齐墩果酸二元酸单酯二钠的合成．齐墩果酸与二元酸内酐作用生成其单酯，然后转化成双钠盐．这一类前体药物在水中溶解度比齐墩果酸增大数千倍
Reported the synthesis of 4 oleanolic acid dibasic monoester disodium. Oleanolic acid and dibasic acid anhydride to generate its monoester, and then converted into bis-sodium salt. This class of prodrugs has thousands of times more solubility in water than oleanolic acid